USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: TRAP1_HUMAN USC-OGP 2-DE database:  TRAP1_HUMAN TRAP1_HUMAN General information about the entry View entry in simple text format Entry name TRAP1_HUMAN Primary accession number Q12931 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Heat shock protein 75 kDa, mitochondrial; Short=HSP 75; AltName: Full=TNFR-associated protein 1; AltName: Full=Tumor necrosis factor type 1 receptor-associated protein; Short=TRAP-1; Flags: Precursor;. Gene name Name=TRAP1 Synonyms=HSP75 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1111: pI=5.20; Mw=104418 Cross-references UniProtKB/Swiss-Prot Q12931; TRAP1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name TRAP1_HUMAN Primary accession number Q12931 Secondary accession number(s) B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 Sequence was last modified on  June 7, 2005 (version 3) Annotations were last modified on  March 15, 2017 (version 174) Name and origin of the protein Description RecName: Full=Heat shock protein 75 kDa, mitochondrial; Short=HSP 75; AltName: Full=TNFR-associated protein 1; AltName: Full=Tumor necrosis factor type 1 receptor-associated protein; Short=TRAP-1; Flags: Precursor; Gene name Name=TRAP1 Synonyms=HSP75 Encoded on Name=TRAP1; Synonyms=HSP75 Keywords 3D-structure; Acetylation; Alternative splicing; ATP-binding; Chaperone; Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome; Transit peptide. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF154108; AAF15314.1; -; mRNA EMBL AK299127; BAG61180.1; -; mRNA EMBL AC005203; AAC24722.1; -; Genomic_DNA EMBL AC006111; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471112; EAW85338.1; -; Genomic_DNA EMBL CH471112; EAW85340.1; -; Genomic_DNA EMBL BC018950; AAH18950.1; -; mRNA EMBL BC023585; AAH23585.1; -; mRNA EMBL U12595; AAA87704.1; ALT_FRAME; mRNA EMBL AF043254; AAC02679.1; -; mRNA CCDS CCDS10508.1; -. [Q12931-1]; . CCDS CCDS61824.1; -. [Q12931-2]; . RefSeq NP_001258978.1; NM_001272049.1. [Q12931-2]; . RefSeq NP_057376.2; NM_016292.2. [Q12931-1]; . UniGene Hs.30345; -; . PDB 4Z1F; X-ray; 2.70 A; A=60-561 PDB 4Z1G; X-ray; 3.10 A; A=60-561 PDB 4Z1H; X-ray; 2.90 A; A=60-561 PDB 4Z1I; X-ray; 3.30 A; A/B/C/D=60-561 PDB 5F3K; X-ray; 1.82 A; A/B=60-294 PDB 5F5R; X-ray; 1.85 A; A/B=60-294 PDB 5HPH; X-ray; 2.43 A; A/B=60-554 PDBsum 4Z1F; -; . PDBsum 4Z1G; -; . PDBsum 4Z1H; -; . PDBsum 4Z1I; -; . PDBsum 5F3K; -; . PDBsum 5F5R; -; . PDBsum 5HPH; -; . ProteinModelPortal Q12931; -; . SMR Q12931; -; . BioGrid 115435; 78; . DIP DIP-6250N; -; . IntAct Q12931; 39; . MINT MINT-1510364; -; . STRING 9606.ENSP00000246957; -; . BindingDB Q12931; -; . ChEMBL CHEMBL1075132; -; . GuidetoPHARMACOLOGY 2909; -; . iPTMnet Q12931; -; . PhosphoSitePlus Q12931; -; . SwissPalm Q12931; -; . BioMuta TRAP1; -; . DMDM 67477458; -; . REPRODUCTION-2DPAGE IPI00030275; -; . EPD Q12931; -; . MaxQB Q12931; -; . PaxDb Q12931; -; . PeptideAtlas Q12931; -; . PRIDE Q12931; -; . Ensembl ENST00000246957; ENSP00000246957; ENSG00000126602. [Q12931-1]; . Ensembl ENST00000538171; ENSP00000442070; ENSG00000126602. [Q12931-2]; . GeneID 10131; -; . KEGG hsa:10131; -; . UCSC uc002cvt.4; human. [Q12931-1]; . CTD 10131; -; . DisGeNET 10131; -; . GeneCards TRAP1; -; . H-InvDB HIX0012776; -; . HGNC HGNC:16264; TRAP1; . HPA HPA041082; -; . HPA HPA044227; -; . MalaCards TRAP1; -; . MIM 606219; gene; . neXtProt NX_Q12931; -; . OpenTargets ENSG00000126602; -; . PharmGKB PA36781; -; . eggNOG KOG0019; Eukaryota; . eggNOG COG0326; LUCA; . GeneTree ENSGT00840000129758; -; . HOGENOM HOG000031987; -; . HOVERGEN HBG103147; -; . InParanoid Q12931; -; . KO K09488; -; . OMA MLLTNMN; -; . OrthoDB EOG091G03C9; -; . PhylomeDB Q12931; -; . TreeFam TF315234; -; . Reactome R-HSA-611105; Respiratory electron transport; . ChiTaRS TRAP1; human; . GeneWiki TRAP1; -; . GenomeRNAi 10131; -; . PRO PR:Q12931; -; . Proteomes UP000005640; Chromosome 16; . Bgee ENSG00000126602; -; . CleanEx HS_TRAP1; -; . ExpressionAtlas Q12931; baseline and differential; . Genevisible Q12931; HS; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005811; C:lipid particle; ISS:ParkinsonsUK-UCL; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB; . GO GO:0005758; C:mitochondrial intermembrane space; ISS:ParkinsonsUK-UCL; . GO GO:0005759; C:mitochondrial matrix; IDA:UniProtKB; . GO GO:0005739; C:mitochondrion; IDA:ParkinsonsUK-UCL; . GO GO:0005654; C:nucleoplasm; IDA:HPA; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0019901; F:protein kinase binding; IPI:ParkinsonsUK-UCL; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0005164; F:tumor necrosis factor receptor binding; NAS:UniProtKB; . GO GO:0061077; P:chaperone-mediated protein folding; TAS:ParkinsonsUK-UCL; . GO GO:1901856; P:negative regulation of cellular respiration; IMP:UniProtKB; . GO GO:1903751; P:negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide; ISS:ParkinsonsUK-UCL; . GO GO:1903427; P:negative regulation of reactive oxygen species biosynthetic process; TAS:ParkinsonsUK-UCL; . GO GO:0006950; P:response to stress; IEA:InterPro; . GO GO:0009386; P:translational attenuation; IMP:CACAO; . Gene3D 3.30.565.10; -; 1; . HAMAP MF_00505; HSP90; 1; . InterPro IPR003594; HATPase_C; . InterPro IPR001404; Hsp90_fam; . InterPro IPR020575; Hsp90_N; . InterPro IPR020568; Ribosomal_S5_D2-typ_fold; . PANTHER PTHR11528; PTHR11528; 1; . Pfam PF00183; HSP90; 1; . PIRSF PIRSF002583; Hsp90; 1; . PRINTS PR00775; HEATSHOCK90; . SMART SM00387; HATPase_c; 1; . SUPFAM SSF54211; SSF54211; 1; . SUPFAM SSF55874; SSF55874; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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